A Facile Fabrication Of Hydroxyapatite In Vitro Using Polymer Fasciculus As Biotemplate Carrier
Tao Yan, Dong Wei, Xianpeng Zheng, Xiaodong Xin, Nuo Zhang, Dan Wu, Liangguo Yan, He Li, Bin Du, Qin Wei
Volume 1, Issue 2, Page 106-113, Year 2010 | DOI: 10.5185/amlett.2010.4111
Biomineralization; hydroxyapatite; polymer fasciculus; biomimetic synthesis
For biomimetic synthesis of hydroxyapatite by simulating biomineralization, the polyamide 66 (PA 66) was used as biotemplate carrier, and the biotemplate was prepared by the adsorption of AOT surfactants at interfaces of polymer fasciculus. Simulating biomineralization was carried out at physiological condition (pH = 7.4, T = 37 oC). The phase components, morphologies and possible growth mechanism of calcium phosphate were studied by fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and scanning electron microscopy (SEM). The results indicated that the course of crystal growth, as well as the morphology and composition of product was markedly dependent on biotemplate; the crystals size were within nanometer scope, with a sphere and short rod-like shape extraordinary close to natural bone. The possible mechanism of crystal growth was discussed. Copyright © 2010 VBRI press.